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Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC50 of 3 nM. Maribavir has potent antiviral activity against HCMV and Epstein-Barr virus (EBV).
Ganciclovir Mono-O-acetate is a ganciclovir (sc-203963) derivative. It is an anti-inflammatory and anti-itching corticosteroid usually present in topical cream.
Letermovir is an anti-CMV compound which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors.
Valganciclovir HCl is the L-valyl ester of ganciclovir, is a prodrug for ganciclovir with antiviral activity used to treat cytomegalovirus infections.
CMX001 was developed as an orally active, lipophilic form of cidofovir (CDV) and has enhanced activity in vitro and in vivo compared to CDV against certain herpesviruses, adenoviruses and orthopoxviruses.
SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM[1]. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity[2].
Floxuridine is an oncology drug that belongs to antimetabolites with an GI50 of 5.1 μM for the inhibition of PEPT1.
Cidofovir is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis, which suppresses virus replication by selective inhibition of viral DNA synthesis.
Cidofovir is an anti-CMV drug which can suppress CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription.
Tags: 巨细胞病毒 | CMV | 抗感染 | Anti-infection | 巨细胞病毒 相关产品
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