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MSC2530818 is a Potent, Selective, and Orally Bioavailable CDK8 inhibitor with CDK8 IC50 = 2.6 nM.
LY2857785 is a potent and selective CDK9 inhibitor and significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines.
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Tags: CDK8 | CDK | CDK8 相关产品 | CDK8 基因表达
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