5,5-Dimethyl-2,4-oxazolidinedione is a cathepsin K inhibitor, it's an anticonvulsant.

Asperglaucide, a natural product isolated and purified from the herbs of Walsura yunnanensis, shows some nematocidal property against M. incognita .

Cathepsin inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.

2-Cyanopyrimidine is a potent and non-selective cysteine protease cathepsin K inhibitor with an IC50 of 170 nM. 2-Cyanopyrimidine is used for osteoporos.

AZD7986 is a second generation reversible covalent, potent and selective DPP1 inhibitor potentially for the treatment of chronic obstructive pulmonary disease (COPD) with predicted human PK properties suitable for once daily human dosing.

CA 074 is an inhibitor of cathepsin B with Ki of 2 - 5 nM.

MDL28170 is a potent, selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25 nM respectively) that does not inhibit trypsin-like serine proteases. MDL28170 rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo.

K777 is an irreversible inhibitor of cysteine protease inhibitor and a antagonist of CCR4.

L 006235 is a potent, reversible cathepsin K inhibitor with IC50 of 0.25 nM.

Leupeptin Hemisulfate is a reversible serine/cysteine protease inhibitor, inhibits cathepsins B, H, L, and S, calpain, and trypsin.

LY 3000328 is a highly selective and potent Cathepsin S inhibitor with IC50 of 7.7±5.85 nM and 1.67±1.17 nM for hCat S and mCat S respectively, can be used in treatment for abdominal aortic aneurysm.

Puromycin aminonucleoside is the aminonucleoside portion of the antibiotic puromycin and it is a puromycin analog which does not inhibit protein synthesis but induces apoptosis.. Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase.

Balicatib is a potent and selective inhibitor of cathepsin K ,with 10-100 fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S.

Odanacatib is a potent, selective, and neutral inhibitor of cathepsin K (human/rabbit) with IC50 of 0.2 nM/1 nM, and demonstrated high selectivity versus off-target cathepsin B, L, S.

CA-074 Methyl Ester is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor.