(-)-Eburnamonine is a vasodilator that also acts as a cerebral metabolic stimulant.

Catharanthine showed muscarinic antagonism at 10 μM and fully inhibited nicotinic receptor mediated diaphragm contractions with an IC50 of 59.6 μM. As a precursor of the anti-tumor drugs vinblastine and vincristine, it also works as an inhibitor of tubulin self-assembly into microtubules.

Vindoline is a natural product isolated and purified from the herbs of Catharanthus roseus (L.) G. Don which can regulate the glucose-stimulated insulin secretion (GSIS), may contribute to the anti-diabetic effects of Catharanthus roseus, and this natural product may find its more applications in the improvement of β-cell dysfunction and further the potential treatment of type 2 diabetes.

Vincristine sulfate is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM.

Vinorelbine inhibits microtubule assembly by inducing tubulin aggregation into spirals and paracrystals.

Vinorelbine is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.

16R-sitsirikine is a natural product isolated and purified from the herbs of Catharanthus roseus.

Vindorosine, a natural product isolated and purified from the herbs of Catharanthus roseus (L.) G. Don, has blood vessel relaxation effect, possible underlying mechanisms involving the inhibition of Ca(2+) entry via L-type Ca(2+) channels in vascular smooth muscles.

Serpentinic acid is a natural product isolated and purified from the herbs of Catharanthus roseus.