LY294002 is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM in cell-free assays. It is an early-stage autophagy inhibitor and also inhibits CK2.

CX-4945 is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively.

DMAT is a potent and specific CK2 inhibitor with an IC50 value of 130 nM.

GO289 is a potent and selective CK2 inhibitor.

BioE-1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. BioE-1115 is also a potent casein kinase 2α inhibitor with an IC50 of ~10 μM .

CX-4945 Sodium is a selective inhibitor of CK2 catalytic subunits with an IC50 value of 1 nmol/L.

TTP 22 is a high affinity, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50/Ki of 0.1 μM/40 nM, showing selectivity for CK2 over JNK3, ROCK1, and MET (IC50> 10 μM).

TBB is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 μM for rat liver and human recombinant CK2 respectively).

DRB is a chemical compound that inhibits transcription elongation by RNA Polymerase II. It works as a transcription inhibitor.