Methyclothiazide is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease.

2-Aminobenzenesulfonamide is a potent inhibitor of carbonic anhydrase B.

Mafenide HCl is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as a topical anti-bacterial agent, especially in burn therapy.

Benzenesulfonamide ia an inhibitor of carbonic anhydrases.

S4 is a selective inhibitor of CA IX and CA XII inhibitor. The Ki values are 2, 7, 547 and 5600 nM for CA XII, IX, II and I, respectively.

EMAC10101d is a potent and selective Carbonic Anhydrase II inhibitor.

Sultiame is an inhibitor of carbonic anhydrase that used to treat epilepsy.

Tioxolone, a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM, is an anti-acne preparation.

U-104 is a potent carbonic anhydrase (CA) inhibitor with Ki of 45.1 nM and 4.5 nM for CA IX and CA XII, respectively.

Dimethylfraxetin is a natural product isolated and purified from the herbs of Viola yedonensis Makino with anti-HRV-2 activity.

Dichlorphenamide is a sulfonamide and an orally bioavailable carbonic anhydrase (CA) inhibitor with Kis of 1.20, 38, 50, and 50 nM for the human CA isoforms CAI, CAII, CAIX, and CAXII, respectively.

Diclazuril is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.

Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.

Dorzolomide HCl is a potent and water-soluble inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM respectively and used as anti-glaucoma agent.

CC-122, also known as avadomide, binds to CRBN and induces degradation of aiolos and ikaros that result in cell apoptosis. It is a antitumor and immunomodulatory agent used to treat DLBCL.