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货号 产品名 纯度
A109921 现货 (E)-KN-93 phosphate

KN-93 Phosphate, a potent Ca2+/calmodulin-dependent protein kinase II (CaMKII) selective inhibitor with Ki of 370 nM, is the water soluble version of KN-93.

99%
A349509 现货 KN-92 phosphate

KN-92 phosphate is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM).

99%
A1155027 现货 Cabamiquine

DDD107498 is a multiple-stage antimalarial agent targeting on eEF2.

99%
A469420 现货 KN-93 HCl

KN-93 HCl is a membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM.

99%
A170870 现货 KN-93

KN-93 is a potent Ca2+/calmodulin-dependent protein kinase II (CaMKII) selective inhibitor with Ki of 370 nM.

99%
A210855 现货 STO-609

STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kinase (CaM-KK) that inhibits the activities of recombinant CaM-KKα and CaM-KKβ isoforms, with Ki values of 80 and 15 ng/mL, respectively, and also inhibits their autophosphorylation activities.

99%
A784014 现货 Calmidazolium chloride

Calmidazolium Chloride is a calmodulin antagonist.

99%
A1499803 现货 Pactimibe sulfate

98%
A964846 现货 W-7 isomer HCl

Calmodulin antagonist

99%
A463272 现货 W-13 HCl

Calmodulin antagonist

99%
A407328 现货 Melittin/蜂毒肽

Melittin can bind calmodulin in a Ca2+-dependent manner and inhibit Na+-K+-ATPase that plays a vital role in Epilepsy treatment.

99%
A506178 现货 DCP-LA

FR 236924 is a selective PKCε activator.

98%
A145417 现货 Berbamine/小檗胺

Berbamine, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII.

99%
A1549973 现货 Cabamiquine succinate

99%
A884358 现货 Autocamtide-2-related inhibitory peptide, myristoylated

Autocamtide-2-related Inhibitory Peptide, myristoylated is a CaM kinase II inhibitor that enhances cell permeable derivative of Autocamtide-2-related inhibitory peptide.

96%
A1364532 现货 XST-14

99%
A455366 现货 KN-62

KN-62 is a selective and potent inhibitor of calmodulin-dependent protein kinase II (CaMK-II) with IC50 of 0.9 μM, KN-62 also displays noncompetitive antagonism at P2X7 receptors in HEK293 cells, with an IC50 value of approximately 15 nM..

99%
A537893 现货 A-484954

99%
A261079 现货 NH125

NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, also a potent histidine kinase inhibitor.

99%
A242790 现货 Berbamine 2HCl/盐酸小檗胺

Berbamine 2HCl, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII.

99%
产品名 CaMKII CaMKIII CaMKKα CaMKKβ PKD 其他靶点 纯度
KN-62 +

CaMKII, Ki: 0.9 μM

99%
KN-93 ++

CaMKII, Ki: 0.37 μM

99%
NH125 +++

eEF-2 kinase, IC50: 60 nM

99%+
STO-609 ++

CaM-KKα, Ki: 0.25 μM

++++

CaM-KKβ, Ki: 47 nM

98%
CID755673 +++

PKD2, IC50: 227 nM

PKD1, IC50: 180 nM

99%+
CRT0066101 2HCl ++++

PKD2, IC50: 2 nM

PKD1, IC50: 1 nM

99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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