Bax inhibitor peptide V5 is a Bax-mediated apoptosis inhibitor, used for cancer treatment.

AMG-176 is an inhibitor of induced myeloid leukemia cell differentiation protein MCL-1 (myeloid cell leukemia-1), with potential pro-apoptotic and antineoplastic activities.

MIK665 is an inhibitor of induced myeloid leukemia cell differentiation protein (Mcl-1; Bcl2-L-3), with potential pro-apoptotic and antineoplastic activities.

S63845 specifically binds with high affinity to the BH3-binding groove of MCL1. S63845 potently kills MCL1-dependent cancer cells, including multiple myeloma, leukaemia and lymphoma cells, by activating the BAX/BAK-dependent mitochondrial apoptotic pathway.

A1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 value of 70 nM in Molt-4 cell.

Mcl1-IN-2 is a Mcl-1 inhibitor without reported IC50 value.

Dehydrocorydaline chloride is an alkaloidal that has anti-inflammatory and anti-cancer activities.

ABT-263 is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤1 nM in cell-free assays, but binds more weakly to Mcl-1 and A1.

Sabutoclax is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.

BI-3812 is a BCL6 inhibitor, inhibiting the BTB domain of BCL6, with an IC50 of ≤3 nM.

BAM 7 is a direct and selective activator of proapoptotic Bax with EC50 of 3.3 μM.

CID5721353 is a B-Cell Lymphoma 6 inhibitor (BCL6 inhibitor).

Azoramide is a modulator of the unfolded protein response (UPR) with antidiabetic activity.

A-1210477 is a potent and selective inhibitor of MCL-1, and weakly binds to BCL-2 and BCL-XL, with Ki of 0.45 nM, 132 nM and > 660 nM, respectively.

BH3I-1 is an inhibitor of Bcl-xL with IC50 of 293.95 μM.

Jaceosidin, a methylated trihydroxyflavone, can induce apoptosis in cancer cells via activating Bax and also could block signaling pathways related to inflammation. It is first isolated from the Compositae family.