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Aspirin is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an anti-inflammatory compound that inhibits Cox-1.
AG-490 is a broad-spectrum inhibitor that has several targets including EGFR (IC50 = 2 μM), ErbB2 (IC50 = 13.5 μM), STAT3 and JAK2.
Ranolazine 2HCl is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.
Curcumin is a natural phenolic compound with impressive antioxidant properties.
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of diclofenac.
Clobetasol propionate is a corticosteroid with anti-inflammatory effect and is used to treat various skin disorders.
Medroxyprogesterone acetate, the acetate form of medroxyprogesterone which is a progesterone receptor agonist and a synthetic variant of the human hormone progesterone
Flufenamic Acid is a COX inhibitor and prevents formation of prostaglandins, binds to and reduce the activity of prostaglandin F synthase and activate TRPC6, it is a NSAID drug.
Piroxicam is a selective COX1 inhibitor with anti-inflammatory effects.
Lornoxicam is a COX inhibitor with IC50 of 5 nM and 8 nM for COX1 and 2 respectively. It's a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of various types of pain.
Diclofenac sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation.
Sulfasalazine is a potent and specific NF-κB inhibitor and also inhibits system Xc and induces ferroptosis.
Pravastatin Sodium is a competitive HMG-CoA reductase inhibitor with IC50 value of 5.6 μM.
Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively, used to reduce fever, pain, stiffness, and swelling.
Etodolac is a non-selective inhibitor of COX with IC50 of 53.5 nM, it is a non-steroidal anti-inflammatory compound.
Voriconazole is a second-generation triazole antifungal used to treat serious fungal infections by inhibiting the synthesis of ergosterol, the major sterol of the fungal cell membrane.
Tropicamide is a mAchR M4 antagonist, used to dilate the pupil and help with examination of the eye.
Diacerein is a symptomatic slow-acting medicine in osteoarthritis which can reduce the level of IL-1 receptors leading to fewer receptors to form heterodimer complexes.
4-Biphenylacetic acid is used in the synthesis of gastrosparing non-steroidal antiinflammatory drug as a potential non-steroidal antiinflammatory agent.
Tags: 抗炎 | Anti-inflammation | 小分子阳性药 | Small Molecule Positive Drug | 抗炎 相关产品
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