ETC-1002 is an AMPK activator and increase the level of AMPK phosphorylation.

ZLN024 HCl is an AMPK allosteric activator and activates α1β1γ1 and α2β1γ1 by around 2–2.5 fold with an EC50 of about 1–2 μM.

Norathyriol, a natural product isolated and purified from the herbs of Mangifera indica L., can improve the glucose utilization and insulin sensitivity by up-regulation of the phosphorylation of AMPK. Norathyriol exerts a potent chemopreventive activity by inhibiting Akt activation in neoplastic cell transformation.

ZLN024 is an AMPK allosteric activator and activates α1β1γ1 and α2β1γ1 by around 2–2.5 fold with an EC50 of about 1–2 μM.

A-769662 is a reverible and allosteric activator of AMPK through inhibiting dephosphorylation of AMPK on Thr-172.

AMPK activator; also STAT3 inhibitor

In AML cell lines and primary AML samples, GSK621 markedly increases phosphorylation at AMPKα T172, a marker of AMPK activation.

7-Methoxyisoflavone, an isoflavone derivative, is activator of adenosine monophosphate-activated protein kinase (AMPK).

MK-8722 is a potent, direct, allosteric activator of all twelve mammalian AMPK complexes.

Phillyrin is a naturally occuring AMPK activity enhancer, isolated and purified from the fruits of Forsythia suspensa.

Ginkgolide C can enhance the cardiac function of rats in the body, is a flavone isolated from Ginkgo biloba leaves.

Vaccarin, a natural product isolated and purified from the seeds of Vaccaria segetalis, can significantly promote neovascularization by enhancing protein expression of p-Akt , p‑Erk, and CD31, and may be able to selectively protect vascular endothelium from dysfunction induced by H2O2.