(-)-Eburnamonine is a vasodilator that also acts as a cerebral metabolic stimulant.

Peimine can inhibit the production of inflammatory cytokines induced by LPS and block MAPK and NF-κB signaling pathways. It is purified from the bulbus of fritillaria thunbergii.

Imperialine is a natural product isolated and purified from the bulbus of Fritillaria thunbergii Miq. with antiasthmatic effect,on tracheal M receptor antagonist.

Peimisine is a steroidal alkaloid which is the major biologically active component in Bulbus Fritillariae and possess a variety of toxicological and pharmacological effects on humans.

Peiminine, a natural product isolated and purified from the bulbus of Fritillaria thunbergii Miq., is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.It induces autophagic cell death thus represses colorectal carcinoma tumor growth.

Skimmianin, a natural product isolated and purified from the herbs of Skimmia japonica, is an inhibitor against the Leishmania APRT enzyme and a strong acetylcholinesterase (AChE) inhibitor, and has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats.

Evolitrine is one of the major alkaloids present in sri lankan acronychia pedunculata.

Dehydroevodiamine is an alkaloid isolated from E. rutaecarpa and possesses anti-inflammatory, antiarrhythmic, hypotensive, and anti-amnesic biological activities.

Jatrorrhizine is a protoberberine alkaloid isolated from some plant species like Enantia chlorantha. It can inhibit MAO-A and MAO-B noncompetitively with IC50 value of 4μM and 62μM, respectively. Also, it has antiinflammatory, antimicrobial and antifungal activity.

Dictamnine, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz., has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells, and has antimicrobial activity against bacteria and fungi.

Tetrahydroberberine is an isoquinoline alkaloid isolated and purified from the barks of Phellodendron chinense Schneid. It has micromolar affinity for dopamine D(2) (pK (i) = 6.08) and 5-HT(1A) (pK (i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors(5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK (i) < 5.00).

Berbamine, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII.

Columbamine is a quaternary isoquinoline alkaloid isolated and purified from the roots of Coptis chinensis Franch, shows strong activity with IC50 48.1 µM and exerts anti-proliferative and anti-vasculogenic effects on metastatic human osteosarcoma U2OS cells with low toxicity.

Berberrubine, a natural product isolated and purified from the herbs of Coptis chinensis Franch. with antitumor and antidiabetic activity, dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha.

Berberine HCl is an isoquinoline alkaloid isolated from the herb of Coptis chinensis Franch with anti-inflammatory and anti-diabetic effects.

Berbamine 2HCl, a natural product isolated and purified from the roots of Cocculus orbiculatus (L.) DC., has high binding affinity toward the (GGA)8 G-quadruplex, and is a promising agent to suppress liver cancer growth by targeting CAMKII.

Demethyleneberberine (DMB), a component of CPC, is reported to treat alcoholic liver disease as a novel natural mitochondria-targeted antioxidant.