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货号 产品名 纯度
A1364532 现货 XST-14

99%
A418461 现货 HG-14-10-04

HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM.

99%
A1230191 现货 Ceritinib D7

98%
A499627 现货 CH5424802 analog

98%
A1365569 现货 TL13-22

99%
A1942367 现货 Ficonalkib

98%
A2632652 现货 Zilurgisertib fumarate

99%
A1142474 现货 CEP-28122 mesylate HCl

98%
A151843 现货 Brigatinib/布格替尼

Brigatinib is a selective ALK inhibitor with IC50 value of 0.37nM, and also inhibits ROS1, FLT3, FLT3-D835Y mutant and EGFR less potently.

99%
A846689 现货 ALK-IN-1

AP26113 is an analog of AP26113 which is a potent and selective ALK inhibitor. It is also an inhibitor of EGFR.

99%
A297424 现货 JH-VIII-157-02

JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells.

99%
A524942 现货 ALK inhibitor 2

ALK inhibitor 2 is a selective inhibitor for the ALK kinase.

99%
A215396 现货 NVP-TAE 684

NVP-TAE684 is a potent and selective ALK inhibitor with IC50 of 3 nM in a cell-free assay, 100-fold more sensitive for ALK than InsR.

99%
A958074 现货 6-Demethoxytangeretin/6-去甲氧基三苯甲基黄嘌呤

6-Demethoxytangeretin is a natural product isolated and purified from the herbs of Andrographis paniculata with anti-inflammatory activity.

99%
A764743 现货 Trigonelline HCl/葫芦巴碱盐酸盐

Trigonelline HCl is an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.

99%
A868332 现货 X-376

Ensartinib is a potent inhibitor ofALK, which is used to treat non-small-cell lung cancer.

99%
A1176919 现货 F-1

98%
A1177054 现货 BLU-782

BLU-782 is a potent, selective ALK2 inhibitor that prevents edema and heterotopic bone formation in a FOP mouse model.

96%
A1601157 现货 Iruplinalkib

99%
A2628326 现货 ALK-IN-26

99%
产品名 ALK 其他靶点 纯度
ASP3026 +

ALK, IC50: 3.5 nM

99%+
ALK-IN-1 ++++

ALK, IC50: 0.07 nM

99%
Crizotinib ++++

ROS1, Ki: <0.025 nM

ALK, IC50: 24 nM

98%
Entrectinib 99%+
Brigatinib +++

ROS1, IC50: 1.9 nM

ALK, IC50: 0.37 nM

FLT3 98%
NVP-TAE 684 +

ALK, IC50: 3 nM

99%+
Alectinib ++

ALK (F1174L), IC50: 3.5 nM

ALK, IC50: 1.9 nM

98%
Ceritinib +++

ALK, IC50: 0.2 nM

IGF-1R,Insulin Receptor 98%
GSK1838705A +++

ALK, IC50: 0.5 nM

IGF-1R,Insulin Receptor 98%
AZD-3463 ++

ALK, Ki: 0.75 nM

IGF-1R 99%
Lorlatinib ++++

ROS1, Ki: <0.07 nM

ALK (L1196M), Ki: 0.07 nM

98%
Repotrectinib +

ALK(G1202R), IC50: 1.26 nM

ALK(L1196M), IC50: 1.01 nM

Src 99%
Belizatinib ++

ALK, IC50: 0.7 nM

99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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