Benvitimod is a non-steroidal anti-inflammatory drug (NSAID) potentially for the treatment of atopic dermatitis.

Aryl Hydrocarbon Receptor (AhR) Agonists, Signal Transduction Modulators

Aryl Hydrocarbon Receptor (AhR) Agonists, Signal Transduction Modulators

UM729 is an enhancer of aryl hydrocarbon receptor (AhR) antagonists.

DiMNF is a selective aryl hydrocarbon receptor (AHR) modulator (SAhRM).

GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with IC50 of 62 nM.

StemRegenin 1 is an AhR antagonist with IC50 of 127 nM. Also, it stimulates the proliferation and differentiation of CD34+ hematopoietic progenitor cells.

Aryl Hydrocarbon Receptor (AhR) Agonists, Signal Transduction Modulators

ITE is an AhR agonist with Ki value of 3nM, and also inhibits TGF-β-induced human myofibroblast differentiation.

CH-223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor.

1,4-Chrysenequinone, a polycyclic aromatic quinone, acts as an activator of aryl hydrocarbon receptor (AhR).

Cardamonin (Cardamomin), a natural flavone isolated from Alpinia katsumadai Hayata, acts as an aryl hydrocarbon receptor (AhR) activator. Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway .